The A1079 Hull to York route has been closed both ways following a road traffic collision involving a car and a van.
Humberside Police officers were called out to the incident today (Friday 4 May) at around 1.15pm.
Humberside Fire Service also attended the incident with its specialist Rescue Support Unit, based at Clough Road in Hull, called to the scene.
A police spokesman said: “Our officers were called to the collision on Hull Road involving a car and a van.
“Motorists should avoid the area around the A1079 at Wilberfoss if at all possible for the time being.”
The spokesman also added that the air ambulance was also called to the scene.